A selection of recent articles in the field of SMA is provided below. For a complete listing of SMA research articles, please visit PubMed.

Electrical impedance myography in spinal muscular atrophy: A longitudinal study. Rutkove SB, Gregas MC, Darras BT. Muscle Nerve. 2012 May;45(5):642-7.

Childhood spinal muscular atrophy: controversies and challenges. Mercuri E, Bertini E, Iannaccone ST. Lancet Neurol. 2012 May; 11(5):443-52.

Evaluation of SMN Protein, Transcript, and Copy Number in the Biomarkers for Spinal Muscular Atrophy (BforSMA) Clinical Study. Crawford TO, Paushkin SV, Kobayashi DT, Forrest SJ, Joyce CL, et al. PLoS ONE. 2012 Apr 27;7(4): e33572.

Candidate Proteins, Metabolites and Transcripts in the Biomarkers for Spinal Muscular Atrophy (BforSMA) Clinical Study. Finkel RS, Crawford TO, Swoboda KJ, Kaufmann P, Juhasz P, et al. PLoS ONE. 2012 Apr 27;7(4): e35462.

Survival motor neuron affects plastin 3 protein levels leading to motor defects. Hao le T, Wolman M, Granato M, Beattie CE. J Neurosci. 2012 Apr 11;32(15):5074-84.

Age at Disease Onset Predicts Likelihood and Rapidity of Growth Failure Among Infants and Young Children With Spinal Muscular Atrophy Types 1 and 2. Sproule DM, Hasnain R, Koenigsberger D, Montgomery M, De Vivo DC, Kaufmann P. J Child Neurol. 2012 Mar 30.

Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophy. Melissa Bowerman, Lyndsay M Murray, Justin G Boyer, Carrie L Anderson, Rashmi Kothary. BMC Medicine. 2012 Mar 7.

Spinal muscular atrophy: a clinical and research update. Markowitz JA, Singh P, Darras BT. Pediatr Neurol. 2012 Jan. 46(1):1-12.

Spinal Muscular Atrophy Type III: Trying to Understand Subtle Functional Change Over Time–A Case Report. Dunaway S, Montes J, Ryan PA, Montgomery M, Sproule DM, De Vivo DC. J Child Neurol. 2011 Dec 7.

Validation of the Children’s Hospital of Philadelphia Infant Test of Neuromuscular Disorders (CHOP INTEND). Glanzman AM, McDermott MP, Montes J, Martens WB, Flickinger J, Riley S, Quigley J, Dunaway S, Oʼhagen J, Deng L, Chung WK, Tawil R, Darras BT, Yang M, Sproule D, De Vivo DC, Kaufmann P, Finkel RS. Pediatr Phys Ther. 2011 Dec;26(12):1499-507.

Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model. Hua Y, Sahashi K, Rigo F, Hung G, Horev G, Bennett CF, Krainer AR. Nature. 2011 Oct 5;478(7367):123-6.