Drugs Discovery Assets:

In Vivo Testing

SMA Foundation

The SMA Foundation maintains an in vivo drug testing pipeline, where compounds are screened for their efficacy using a standardized platform in a model of severe SMA, the Delta7 mouse, and more recently in the C/C mouse that models milder forms of SMA. We have tested over 160 experimental compounds and approved drugs in this testing pipeline at PsychoGenics (PGI). Please see the SMA Foundation report on our mouse drug testing pipeline, for a summary of results and available resources.

For more information, please contact researchtools@smafoundation.org.